Telomeric (TTAGGG)n sequences are associated with nucleolus organizer regions (NORs) in the wood lemming
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Updated: Aug 7, 2026

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1Department of Conservation Biology and Genetics, Uppsala University, Uppsala Genetic Centre, Sweden. wansheng.liu@genetik.uu.se
Abstract:
The distribution of the (TTAGGG)n telomeric sequence was studied in chromosomes of the wood lemming, Myopus schisticolor, by fluorescence in-situ hybridization. As expected, the hybridization signals were observed at telomeres of all chromosomes. However, quite a number of interstitial telomeric sites were present in the pericentric heterochromatic regions. Consistent strong hybridization signals were also seen at one terminus of chromosomes 5, 7 and 12--15. By post-hybridization G-banding and silver-staining, the large blocks of the telomeric sequences on chromosomes 5 and 12 were localized to nucleolus organizer regions (NORs).
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