Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synchronizing dynamic multileaf collimators for producing two-dimensional intensity-modulated fields with minimum

L Ma1, A L Boyer, C M Ma

  • 1Department of Radiation Oncology, Stanford University School of Medicine, CA 94305, USA.

International Journal of Radiation Oncology, Biology, Physics
|July 27, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Handcrafted firearm suicide: About the unusual use of a mole gun.

Legal medicine (Tokyo, Japan)·2022
Same author

[ABO gene subtypes and gene expression analysis in three cases of hematological malignancies patients].

Zhonghua yi xue za zhi·2020
Same author

Cytotoxic constituents of Lasiosphaera fenzlii on different cell lines and the synergistic effects with paclitaxel.

Natural product research·2015
Same author

Quantification and antioxidant and anti-HCV activities of the constituents from the inflorescences of Scabiosa comosa and S. tschilliensis.

Natural product research·2015
Same author

Comparison of IMRT and Rapidarc treatment plans using AAPM task group test suites.

The Gulf journal of oncology·2011
Same author

How to simplify the diagnostic criteria of hypertension in adolescents.

Journal of human hypertension·2010

Synchronizing dynamic multileaf collimator (DMLC) leaf motion in intensity-modulated radiotherapy (IMRT) minimizes beam delivery time and subfield variations. This optimized approach ensures efficient and precise treatment delivery for complex intensity profiles.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Technology

Background:

  • Dynamic multileaf collimators (DMLC) are crucial for intensity-modulated radiotherapy (IMRT).
  • Leaf motion synchronization in DMLC improves dose distribution and reduces "tongue-and-groove" effects.
  • Synchronization enables the transformation of 1D leaf-setting algorithms to 2D.

Purpose of the Study:

  • To develop a generalized leaf synchronization method for DMLC in IMRT.
  • To minimize beam delivery time and optimize subfield variations for leaf-setting sequences.
  • To achieve efficient delivery of prescribed intensity profiles.

Main Methods:

  • Synchronized all active MLC leaf pairs to start and finish simultaneously.
  • Determined synchronization parameters via least-square minimization of subfield area variations.

Related Experiment Videos

  • Applied and analyzed the synchronization and optimization procedure for head-and-neck cancer patient IMRT profiles.

    • Main Results:

    • Achieved global minimum for total monitor units and beam delivery time for 2D intensity profiles.
    • Demonstrated that synchronized leaf trajectories have significantly smaller subfield variations compared to unsynchronized ones.
    • Found the optimal synchronization parameter to be intensity-profile dependent.

    Conclusions:

    • Synchronizing and optimizing DMLC leaf motion is feasible and essential for IMRT.
    • This method allows for minimum total beam delivery time while delivering arbitrary 2D intensity-modulated fields.
    • Optimized synchronization enhances treatment precision and efficiency.