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Identification of Kinase-substrate Pairs Using High Throughput Screening
Published on: August 29, 2015
Kinase phosphorylation: Keeping it all in the family
1Howard Hughes Medical Institute, Departments of Chemistry and Chemical Biology and Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Current Biology : CB
|July 27, 1999
Abstract:
The identification of PDK1 as a kinase that phosphorylates the AGC family of kinases led to a hunt for 'PDK2', a hypothetical regulated kinase(s) that would be required for full activation of the AGC kinases. Recent findings suggest that the elusive PDK2 may actually be a familiar kinase with an atypical associate.
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