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[Nucleotide sequence of rat tyrosine aminotransferase gene]

I V Morozov1, F O Smagulova, N V Soshnikova

  • 1Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, Russia. mor@niboch.nsc.ru

Bioorganicheskaia Khimiia
|July 28, 1999
PubMed

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Transfer RNA Synthesis02:36

Transfer RNA Synthesis

One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...