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Cervical verrucous carcinoma involving endometrium. Case report
E Szczepulska1, A Nasierowska-Guttmejer, M Bidziński
1Department of Pathology Oncological Centre, Warsaw, Poland.
European Journal of Gynaecological Oncology
|July 28, 1999
Summary
This case report details a rare verrucous carcinoma of the cervix, a variant of squamous cell carcinoma with a good prognosis. Treatment involved hysterectomy, ovary transposition, and brachytherapy, followed by a five-year disease-free observation.
Area of Science:
- Gynecology
- Oncology
- Pathology
Background:
- Verrucous carcinoma is a rare, distinct variant of squamous cell carcinoma.
- It typically presents with a favorable prognosis compared to other squamous cell carcinomas.
- Accurate histopathological assessment is crucial for diagnosis, as superficial biopsies can be misleading.
Observation:
- A case of verrucous carcinoma of the cervix in a 32-year-old woman is presented.
- The patient underwent abdominal hysterectomy with bilateral ovary transposition.
- Intravaginal brachytherapy with Cesium-137 was administered to a total dose of 60 Gy.
- A five-year disease-free follow-up was achieved.
Findings:
- Macro- and microscopic examination post-hysterectomy confirmed the diagnosis.
- The importance of full-thickness tumor assessment for accurate histopathological diagnosis was highlighted.
- Differential diagnosis from condyloma acuminata and invasive squamous cell carcinoma was analyzed.
Implications:
- This case underscores the importance of thorough histopathological evaluation for verrucous carcinoma of the cervix.
- It demonstrates a successful treatment approach combining surgery and brachytherapy.
- Accurate diagnosis is vital to avoid misclassification and ensure appropriate management, distinguishing it from more aggressive squamous cell carcinomas.