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Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1
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Phosphorylation by CDK1 regulates XMAP215 function in vitro

R J Vasquez1, D L Gard, L Cassimeris

  • 1Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015, USA.

Cell Motility and the Cytoskeleton
|July 28, 1999
PubMed
Summary

XMAP215 protein enhances microtubule dynamics, particularly plus-end elongation. Phosphorylation by CDK1 reduces this elongation-promoting effect, suggesting cell cycle regulation of microtubule assembly.

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