[The atherogenesis characteristics of diabetic patients]

A total of 154 patients with type-I insulin-nondependent diabetes mellitus were examined together with 222 patients presenting with type-II insulin-nondependent diabetes mellitus. In glycemia of up to 6.66 mmol/l the level of blood plasma cholesterol was (5.40 +/- 0.02) mmol/l; with 7.77 mmol/l it came up to (6.33 +/- 0.02) mmol/l. Correlation has been shown to exist between fast glycemia and decline in the HDLP levels of cholesterol and rise in the atherogenicity factor. The content of MDA in plasma, LDLP + VLDLP, erythrocytes appeared to be related to the content of glycosylated hemoglobin. The author arrives at a conclusion that decompensation of DM is the most important factor of atherogenesis, attainment of a stable compensation is an essential condition of prevention of atherosclerosis further development in DM patients.