Related Experiment Video
Updated: Oct 2, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
[The characteristics of the local protective factors in disseminated suppurative peritonitis]
Abstract:
A comparative evaluation was done of factors of the local and systemic immunity in 18 patients with diffuse pyoperitonitis. Morphological (neutrophiles from the abdominal cavity in patients with peritonitis retrieve NBT in a diffuse-dotted fashion whereas neutrophiles of blood give a diffuse pattern and by granules) and functional (reduced metabolic activity of abdominal neutrophiles in a spontaneous NBT-test and an augmented index for the reserve versus metabolic activity of blood neutrophiles) differences in local and systemic factors of immune defence were noted. It is shown that the content of all classes of immunoglobulins is significantly lower in the peritoneal exudate than it is in blood serum. The above facts are to be considered in treatment of patients with generalized purulent peritonitis.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Determinants of Bacterial Pathogenicity and Virulence
Acute Inflammation III: Local and Systemic Effects
Inflammatory Bowel Disease III: Crohn's Disease
Appendicitis

