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Beta-amyloid: Alzheimer's disease and brain beta-amyloidoses
N V Koudinova1, T T Berezov, A R Koudinov
1Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119832, Russia. inst@ibmh.msk.su
Biochemistry. Biokhimiia
|July 29, 1999
Abstract:
This review considers some aspects of the biochemistry of beta-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of beta-amyloid as of a normal human protein is presented.