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Development and validation of an objective method of determining skin erythema to transdermal oestradiol patches

D Ross1, M Whitehead, B Pike

  • 1Menopause Clinic, King's College Hospital, London, UK.

British Journal of Obstetrics and Gynaecology
|July 30, 1999
PubMed
Abstract

No abstract available in PubMed .

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Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...

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