Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Scleromyxedema.

Z Bata-Csorgo1, S Husz, M Foldes

  • 1Department of Dermatology, Albert Szent-Gyorgyi Medical University, Szeged, Hungary.

Journal of the American Academy of Dermatology
|July 30, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patterns of Mammography Screening in Women with Breast Cancer in a Kansas Community.

Preventive medicine and community health·2023
Same author

Evidence of the American <i>Myxobolus dechtiari</i> was introduced along with its host <i>Lepomis gibbosus</i> in Europe: Molecular and histological data.

International journal for parasitology. Parasites and wildlife·2021
Same author

Is it Necessary to Perform Sentinel Lymph Node Biopsy in Thin Melanoma? A Retrospective Single Center Analysis.

Pathology oncology research : POR·2019
Same author

Differential survival of 3rd stage larvae of Contracaecum rudolphii type B infecting common bream (Abramis brama) and common carp (Cyprinus carpio).

Parasitology research·2019
Same author

Adjunctive role of manual lymph drainage in the healing of venous ulcers: A comparative pilot study.

Lymphology·2019
Same author

Pioneers in Dermatology and Venereology: An Interview with Prof. Attila Dobozy.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same journal

Localized radiation therapy provides more durable disease control than topical steroids in stage IA mycosis fungoides.

Journal of the American Academy of Dermatology·2026
Same journal

Atypical fibroxanthoma, pleomorphic dermal sarcoma, and undifferentiated sarcoma: Updates on diagnosis, management, and surveillance.

Journal of the American Academy of Dermatology·2026
Same journal

Response to Li et al., "Comment on Nie et al. (2026) 'Suicidality Reports in Acne Patients Treated with Isotretinoin and Concomitant Antidepressants: A Descriptive Analysis of FDA Adverse Event Reporting System Data'".

Journal of the American Academy of Dermatology·2026
Same journal

Treatment Utilization Patterns in Cutaneous Lupus Erythematosus: A Single-Center Retrospective Analysis.

Journal of the American Academy of Dermatology·2026
Same journal

Hypoactive Sexual Desire Disorder in Menopausal Women: Dermatologic Implications of Antiandrogen and Testosterone Therapy.

Journal of the American Academy of Dermatology·2026
Same journal

Incise parallel, section perpendicular to the dermatoglyphs for diagnosis of acral melanocytic lesions-A comment on Thakker et al.

Journal of the American Academy of Dermatology·2026
See all related articles

Scleromyxedema, a rare skin condition, can present with systemic sclerosis-like illness and myositis. Cyclosporin treatment showed promise in managing this complex case.

Area of Science:

  • Dermatology
  • Rheumatology
  • Immunology

Background:

  • Scleromyxedema is a rare sclerotic variant of papular mucinosis.
  • It is characterized by lichenoid papules and scleroderma-like skin changes.

Observation:

  • A patient presented with scleromyxedema, IgG lambda paraproteinemia, systemic sclerosis-like illness, and myositis.
  • Serum analysis revealed Scl 70 antibodies, and electromyography indicated acute myositis with elevated creatine phosphokinase (CPK).
  • In vitro studies demonstrated altered growth patterns in patient-derived fibroblasts from skin lesions.

Findings:

  • The patient exhibited a complex presentation of scleromyxedema with overlapping systemic features.
  • Diagnostic workup confirmed the presence of specific autoantibodies and markers of muscle inflammation.

Related Experiment Videos

  • Fibroblast cultures provided insights into the cellularpathology of the skin lesions.

    • Implications:

    • This case highlights the potential systemic involvement in scleromyxedema, including myositis and features mimicking systemic sclerosis.
    • The findings underscore the importance of comprehensive evaluation in patients with scleromyxedema.
    • Successful treatment with cyclosporin suggests a potential therapeutic option for severe or systemic cases.