Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small pulmonary nodules: evaluation with repeat CT--preliminary experience.

D F Yankelevitz1, R Gupta, B Zhao

  • 1Department of Radiology, New York Hospital-Cornell University Medical Center, NY 10021, USA. dyankele@mail.med.cornell.edu

Radiology
|August 3, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Curcumin monomer regulates ferroptosis via the melatonin receptor 2/cyclic adenosine monophosphate/protein kinase A/inositol-requiring enzyme 1 pathway to treat ischemic stroke.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2026
Same author

[Popularity characteristics of respiratory syncytial virus infection in children aged 5 years and under in Pudong New Area, Shanghai, 2013-2023].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025
Same author

Radiomic signatures to estimate survival in patients with advanced hepatocellular carcinoma treated with sorafenib: Cancer and Leukemia Group B 80802 (Alliance).

ESMO open·2025
Same author

[The clinical and imaging presentations of the pontine tegmental cap dysplasia].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2025
Same author

Unravelling the molecular recognition mechanism between odorants and PBP1 in <i>Loxostege sticticalis</i> by homology modelling, molecular docking, and MD simulation.

SAR and QSAR in environmental research·2025
Same author

[Research progress in diabetic lumbosacral radiculoplexus neuropathy].

Zhonghua nei ke za zhi·2025
Same journal

Noncontrast Abbreviated MRI for Post-TACE Treatment Response Monitoring of Hepatocellular Carcinoma Based on Ancillary Features from LI-RADS.

Radiology·2026
Same journal

Response Evaluation Criteria in Bone Metastases: Performance and Association of Response Classifications with Survival Outcomes.

Radiology·2026
Same journal

Entropy for Prediction of MACEs in Myocarditis: A Cardiac MRI-based Biomarker of Myocardial Tissue Heterogeneity.

Radiology·2026
Same journal

AI for Radiology: A Primer Part II. Interacting with AI Results.

Radiology·2026
Same journal

Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT Trial Post Hoc Analysis.

Radiology·2026
Same journal

Sawtooth Cardiomyopathy: The Tiger Heart.

Radiology·2026
See all related articles

Early repeat computed tomography (CT) can detect solitary pulmonary nodule growth within 30 days. This method accurately classified all 15 nodules, aiding in the early detection of malignant tumors.

Area of Science:

  • Radiology
  • Pulmonary Medicine
  • Oncology

Background:

  • Solitary pulmonary nodules require accurate assessment for growth to differentiate benign from malignant conditions.
  • Early detection of malignant pulmonary nodules is crucial for timely and effective treatment.

Purpose of the Study:

  • To evaluate the efficacy of early repeat computed tomography (CT) in detecting growth of solitary pulmonary nodules.
  • To determine the optimal timing for repeat CT scans to assess nodule progression.

Main Methods:

  • Nodule phantoms were used to validate a measurement technique for assessing area change.
  • A cohort of 15 patients with solitary pulmonary nodules underwent repeat CT scans as part of routine clinical management.
  • Nodule growth was assessed using the validated technique, with final diagnoses confirmed by surgical resection or long-term follow-up.

Related Experiment Videos

Main Results:

  • Phantom experiments demonstrated that the area change measurement technique is sensitive to minimal nodule growth.
  • In vivo, malignant nodule growth was detectable within 30 days using standard exponential growth models.
  • Early repeat CT correctly classified all 15 studied pulmonary nodules, distinguishing between growth patterns.

Conclusions:

  • A single repeat CT scan, performed approximately 30 days after the initial scan, can effectively identify growth in most malignant solitary pulmonary nodules.
  • This approach shows promise for the early diagnosis of small (≥5 mm) malignant pulmonary tumors.