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Updated: Oct 19, 2026
Evaluation of Synaptic Multiplicity Using Whole-cell Patch-clamp Electrophysiology
Published on: April 23, 2019
Studies of the relationship between ultrastructural synaptic plasticity and ribosome number in dendritic terminals in
1Department of Higher Nervous Activity, M. V. Lomonosov Moscow State University.
Abstract:
The relationship between structural changes in postsynaptic densities of axodendritic synapses and the sizes of postsynaptic ribosomal aggregations were studied. A positive correlation was found between the thickness of the postsynaptic density and the number of ribosomes. The role of dendritic mRNA and the possible mechanisms supporting rapid local protein synthesis during the modification of postsynaptic components is seen on combined administration of two neuromediators into the rat neocortex.
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