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Synthesis and antiviral activity of D- and L-isodideoxy nucleosides with exocyclic-methylene
1Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul, Korea.
Nucleosides & Nucleotides
|August 5, 1999
Abstract:
Novel D- and L-isodideoxynucleosides were synthesized starting from D- and L-xylose and evaluated for antiviral activities against HIV-1, HSV-1, HSV-2, HBV and HCMV, respectively.