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Vibrational study of a nucleoside analogue with antiviral activity, 5-chloro-2'-deoxyuridine, CDU
L Bailey1, R Navarro, A Hernanz
1Departamento de Ciencias y Técnicas Fisicoquímicas, UNED, Madrid, Spain.
Nucleosides & Nucleotides
|August 5, 1999
Abstract:
The experimental FTIR and FT-Raman spectra of 5-chloro-2'-deoxyuridine have been assigned on the basis of normal coordinate analyses, in the light of observed and calculated wavenumbers and isotopic shifts. The results indicate that virtually all normal modes of IDU involve some degree of vibrational coupling between the chlorouracil base and the deoxyribose moiety.