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Related Experiment Video

Updated: Jul 24, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [¹³C]-octanoic Acid Breath Test

Published on: March 23, 2013

Gastric emptying in trauma patients.

C B Carlin¹, P H Scanlon, D A Wagner

¹Department of Medical Education, Carraway Methodist Medical Center, Birmingham, AL, USA.

Digestive Surgery

|August 7, 1999

Summary

Trauma patients exhibit delayed gastric emptying, with minimal recovery within a week. Early nutritional support should utilize transpyloric feeding rather than gastric feeding due to impaired gastric emptying.

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Published on: August 22, 2025

Area of Science:

Gastroenterology
Trauma Medicine
Nutritional Support

Background:

Gastric emptying is crucial for effective enteral nutrition.
Trauma can significantly impact gastrointestinal function.
Quantitative data on post-trauma gastric emptying is limited.

Purpose of the Study:

To quantify gastric emptying in trauma patients.
To assess the recovery of gastric emptying over one week post-trauma.
To inform optimal timing and route for early nutritional intervention in trauma.

Main Methods:

Utilized L-[1-(13)C]phenylalanine absorption to measure gastric emptying.
Administered L-[1-(13)C]phenylalanine nasogastrically to 14 trauma patients.
Measured plasma enrichment and expired (13)CO(2) at 24 hours and 7 days post-admission.

Main Results:

Significantly delayed gastric emptying observed in trauma patients compared to controls.
A fivefold increase in plasma L-[1-(13)C]phenylalanine enrichment noted from initial to second study.
Over a sixfold increase in (13)CO(2) exhalation, indicating improved but still limited gastric emptying after 7 days.

Conclusions:

Gastric emptying is significantly delayed in trauma patients with slow recovery.
Gastric feeding is not recommended for early nutritional support in trauma.
Transpyloric feeding is the preferred route for early nutritional intervention in trauma patients.