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Cystic pancreatic neoplasms.

D W Rattner1, C Fernandez-del Castillo, A L Warshaw

  • 1Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, USA. Rattner.David@mgh.harvard.edu

Annals of Oncology : Official Journal of the European Society for Medical Oncology
|August 7, 1999
PubMed
Summary

Cystic pancreatic neoplasms vary widely. Serous cystadenomas are benign, but mucinous cystic tumors have malignant potential, often requiring surgery for diagnosis and treatment.

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Cystic pancreatic neoplasms are diverse, with mucinous cystic tumors and serous cystadenomas being the most common.
  • Serous cystadenomas are typically benign, whereas mucinous cystic tumors possess malignant potential.

Purpose of the Study:

  • To differentiate between various cystic pancreatic lesions.
  • To outline appropriate diagnostic and treatment strategies for cystic pancreatic neoplasms.

Main Methods:

  • Review of clinical and biochemical features for lesion differentiation.
  • Surgical resection for definitive diagnosis and treatment when indicated.

Main Results:

  • Distinguishing features exist for various cystic pancreatic lesions.

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  • Surgical resection is frequently necessary for accurate diagnosis and management.

    • Conclusions:

    • Mucinous cystic tumors must be managed as potentially malignant.
    • Pancreatic parenchymal-sparing procedures are preferred for benign lesions.
    • Malignant or indeterminate lesions require standard surgical oncologic principles.