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Probiotics or microbes against microbes.

R Zivković

    Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti
    |August 7, 1999
    PubMed
    Summary

    Lactic Acid Bacteria (LAB), also known as biotherapeutic bacteria, show proven clinical benefits for various human health conditions, particularly in children. Research highlights the effectiveness of specific LAB strains like LGG in treating diseases and improving health outcomes.

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    Area of Science:

    • Microbiology
    • Clinical Medicine
    • Human Health

    Background:

    • Lactic Acid Bacteria (LAB) have been studied since 1965 as probiotics or biotherapeutic agents.
    • LAB exhibit antibiotic characteristics, making "biotherapeutic bacteria" a suitable designation.
    • Favorable clinical effects of LAB in various human pathologies, especially in children, are well-documented.

    Purpose of the Study:

    • To provide a historical overview of Lactic Acid Bacteria (LAB) discovery and research.
    • To discuss the therapeutic applications and clinical efficacy of LAB.
    • To highlight specific LAB strains, such as LGG, and their verified health benefits.

    Main Methods:

    • Historical literature review on LAB discovery and research.
    • Analysis of clinical studies demonstrating the effects of LAB on human health.
    • Case descriptions of clinical success with specific LAB strains.

    Main Results:

    • LAB have demonstrated positive clinical effects in various pathologic states, particularly in children.
    • The term "biotherapeutic bacteria" is proposed due to their antibiotic properties.
    • Specific LAB strains, notably Lactobacillus rhamnosus GG (LGG), show scientifically verified therapeutic effects.

    Conclusions:

    • Lactic Acid Bacteria (LAB) possess significant therapeutic potential for human health.
    • The clinical efficacy of LAB, especially LGG, is supported by scientific evidence.
    • LAB, including LGG, are valuable in managing various diseases and are used in food production.

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