Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Global-local processing in schizophrenia: hemispheric asymmetry and symptom-specific interference.

T J Ferman1, M Primeau, D Delis

  • 1Finch University of Health Sciences, Chicago Medical School, USA. ferman.tanis@mayo.edu

Journal of the International Neuropsychological Society : JINS
|August 10, 1999
PubMed
Summary

Schizophrenia patients show altered visual perception, responding faster to local details than global patterns. This supports theories of brain hemisphere over/underactivity, impacting visual processing and attention in schizophrenia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data driven optimization of sexual assault case processing.

Forensic science international. Synergy·2020
Same author

Passive smoking acutely affects the microcirculation in healthy non-smokers.

Microvascular research·2019
Same author

DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients.

European journal of neurology·2015
Same author

Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder.

Sleep medicine·2013
Same author

Pathology and temporal onset of visual hallucinations, misperceptions and family misidentification distinguishes dementia with Lewy bodies from Alzheimer's disease.

Parkinsonism & related disorders·2012
Same author

Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies.

Neurology·2011

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Atypical functional hemispheric asymmetry is hypothesized in schizophrenia.
  • Visual perception and processing efficiency may be affected by this asymmetry.

Purpose of the Study:

  • To test the hypothesis of atypical hemispheric asymmetry in schizophrenia using a visual perception task.
  • To investigate the relationship between symptom severity and perceptual processing patterns.

Main Methods:

  • Utilized the directed global-local paradigm, a measure of visual perception.
  • Compared response times and error rates between schizophrenia patients and a normal control group.
  • Analyzed interference effects based on symptom type and severity.

Related Experiment Videos

Main Results:

  • Schizophrenia group had longer response times but similar error rates (<2%) compared to controls.
  • Schizophrenia patients responded faster to local forms than global forms, unlike controls.
  • High positive symptoms correlated with local interference; negative symptoms did not show significant interference patterns.

Conclusions:

  • Findings support the hypothesis of left hemisphere overactivity and right hemisphere underactivity in schizophrenia.
  • Perceptual processing differences in schizophrenia may be linked to interconnected temporal and frontal systems.
  • Symptom profiles, particularly positive symptoms, influence specific types of perceptual interference.