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The impact of basic fibroblast growth factor on photoreceptor function and morphology

C Gargini1, M S Belfiore, S Bisti

  • 1Istituto di Neurofisiologia, Consiglio Nazionale delle Ricerche, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Universitá di Pisa, Italy.

Investigative Ophthalmology & Visual Science
|August 10, 1999
PubMed
Summary

Basic fibroblast growth factor (bFGF) impacts photoreceptor function by enhancing light response but suppressing signal transmission to inner retinal cells. Upregulated bFGF may contribute to vision loss in photoreceptor dystrophies.

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