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The impact of residual renal function and total body water volume on achieving adequate dialysis in CAPD
1Department of Medicine, The George Washington University Medical Center, Washington, DC 20037, USA.
Aims:
The objective is to evaluate the impact of residual renal function (RRF) and total body water (TBW) on achieving adequate dialysis.
Methods:
Sixty three CAPD patients performing four 2 liter exchanges daily were evaluated for RRF, total weekly Kt/V (TWKt/V), total weekly creatinine clearance (TWCC) and TBW.
Results:
In patients with residual renal function (N = 41), TWKt/V and TWCC were 2.2 +/- 0.8 and 77.4 +/- 24.5 L, respectively. In patients without RRF (N = 22), TWKt/V was 1.6 +/- 0.4 and TWCC 42.6 +/- 9.2 L. TBW correlated negatively with TWKt/V in the group without RRF (r = -0.75, P<0.001).
Conclusion:
It is not possible for larger patients without RRF treated with CAPD (2L x 4 exchanges) to achieve the acceptable targets for TWKt/V and TWCC due to TBW.
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