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A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
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[The effect of influenza virus hemagglutinin on erythrocytes and thrombocytes]

I N Zhilinskaia1, E F Derkachev, L A Liapina

  • 1Institute of Influenza, Russian Academy of Medical Sciences, Saint Petersburg, Russia.

Izvestiia Akademii Nauk. Seriia Biologicheskaia
|August 12, 1999
PubMed

We studied the effect of influenza virus hemagglutinin on the volume of erythrocytes and aggregation activity of thrombocytes. Hemagglutinin proved to increase the erythrocyte volume, which ends in their lysis, and to induce disaggregation of the thrombocytes. The effect of hemagglutinin on the erythrocytes and thrombocytes was dose-dependent.

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