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[Exercise-induced acute renal failure associated with renal vasoconstriction].
S Hisanaga1, N Ueno, H Inagaki
1First Department of Internal Medicine, Miyazaki Medical College, Japan.
Nihon Jinzo Gakkai Shi
|August 12, 1999
Summary
Exercise-induced acute renal failure, characterized by loin pain and nausea, is not rare in young athletes. Prompt recognition and supportive care are crucial for kidney function recovery.
Area of Science:
- Nephrology
- Sports Medicine
- Exercise Physiology
Background:
- Exercise-induced acute renal failure (ARF) without rhabdomyolysis is an underrecognized condition.
- This study investigates six cases of ARF following mild to moderate exercise.
Observation:
- Patients presented with severe loin pain and nausea post-exercise.
- Abdominal CT revealed renal patchy vasoconstriction in most cases.
- Serum and urinary myoglobin levels were not elevated, differentiating it from rhabdomyolysis-associated ARF.
Findings:
- Diagnosed as exercise-induced ARF with loin pain (serum creatinine 1.7-8.6 mg/dl).
- Renal function normalized in 5/6 cases within three weeks with fluid therapy and hemodialysis.
- Two patients developed isolated hyperuricosuric hypouricemia post-recovery.
Implications:
- Exercise-induced ARF, likely due to renal vasoconstriction, may be more common than previously thought.
- Consider ARF in young individuals experiencing loin pain and nausea after exercise, especially those with hypouricemia.
- Further research is needed to elucidate the etiology of exercise-induced renal vasoconstriction.
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