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Global breast cancer mortality statistics.

C Mettlin1

  • 1Roswell Park Cancer Institute, Buffalo, NY, USA.

CA: a Cancer Journal for Clinicians
|August 13, 1999
PubMed
Summary
This summary is machine-generated.

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Breast cancer mortality is declining in industrialized nations due to screening and therapies. Factors like fertility rates and regional differences in diet and culture may influence breast cancer trends.

Area of Science:

  • Oncology
  • Epidemiology

Background:

  • Breast cancer mortality shows declining trends in the US and some industrialized nations.
  • This decline is potentially linked to mammographic screening, early detection, and advanced therapies.
  • Higher fertility rates in post-WWII cohorts may also contribute to observed mortality reductions.

Purpose of the Study:

  • To analyze trends in breast cancer mortality across different global regions.
  • To explore potential contributing factors, including screening, therapies, fertility rates, and lifestyle elements.

Main Methods:

  • Comparative analysis of breast cancer mortality data from various countries.
  • Review of literature on factors influencing breast cancer etiology and survival.

Main Results:

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  • Declining breast cancer mortality observed in the US, Canada, Austria, Germany, and the UK.
  • Favorable trends were not reported in Spain, Portugal, Greece, Hungary, Poland, and Italy.
  • Lowest mortality rates are documented in Asian regions, suggesting potential etiological influences.

Conclusions:

  • Mammographic screening, early detection, and improved treatments are key drivers of reduced breast cancer mortality.
  • Fertility patterns and lifestyle factors (diet, culture, environment) may play significant roles in breast cancer etiology and survival rates.
  • Further research into regional variations and lifestyle factors is warranted to understand and combat breast cancer globally.