Dielectrophoresis of human red cells in microchips

The dielectric properties of human red cells are strongly affected by the applied electric field, especially the frequency. Under the high frequency, the cells are acted on by positive dielectrophoresis (DEP) force and move to the tip region of the interdigitated electrode where the electric field is strongest. The cells are acted on by negative DEP force and aggregated in the "bay" zone between the neighboring electrode castellation tips and the surface of the electrodes. The patterns formed by DEP force are identical with the distribution of the electric field.