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Initial tests with a new cardiac assist device
O Reitan1, H Ohlin, B Peterzén
1Department of Cardiology, University Hospital, Lund, Sweden.
ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|August 13, 1999
Summary
A new minimally invasive cardiac assist device using a propeller pump demonstrated effective circulatory support in bench tests and pig models. This device shows promise for managing hemodynamic deterioration during cardiac interventions.
Area of Science:
- Cardiovascular Engineering
- Biomedical Devices
- Hemodynamics
Background:
- Hemodynamic deterioration can necessitate circulatory support during cardiac interventions.
- Existing support methods may be invasive or insufficient.
- A novel minimally invasive cardiac assist device has been developed.
Purpose of the Study:
- To evaluate the efficiency and hemodynamic effects of a new cardiac assist device prototype.
- To assess the device's performance in bench tests and an animal model.
Main Methods:
- Bench testing involved evaluating pressure generation and flow properties of the catheter pump in a water bath.
- In vivo studies utilized three pigs, with the pump placed in the descending aorta.
- Hemodynamic parameters were recorded at varying propeller speeds and sizes.
Main Results:
- Bench tests showed velocity-dependent pressure generation, achieving over 22 mm Hg.
- Maximum flow rates reached 20 L/min at 12,000 rpm and 27 L/min at 15,000 rpm.
- Animal experiments demonstrated a pressure difference up to 48 mm Hg and increased cardiac output.
Conclusions:
- The new cardiac assist device is efficient both in vitro and in vivo.
- The device effectively supports circulation and alters hemodynamics.
- Performance is directly related to propeller speed and size, indicating potential for clinical application.