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Related Experiment Videos

Initial tests with a new cardiac assist device.

O Reitan1, H Ohlin, B Peterzén

  • 1Department of Cardiology, University Hospital, Lund, Sweden.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|August 13, 1999
PubMed
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A new minimally invasive cardiac assist device using a propeller pump demonstrated effective circulatory support in bench tests and pig models. This device shows promise for managing hemodynamic deterioration during cardiac interventions.

Area of Science:

  • Cardiovascular Engineering
  • Biomedical Devices
  • Hemodynamics

Background:

  • Hemodynamic deterioration can necessitate circulatory support during cardiac interventions.
  • Existing support methods may be invasive or insufficient.
  • A novel minimally invasive cardiac assist device has been developed.

Purpose of the Study:

  • To evaluate the efficiency and hemodynamic effects of a new cardiac assist device prototype.
  • To assess the device's performance in bench tests and an animal model.

Main Methods:

  • Bench testing involved evaluating pressure generation and flow properties of the catheter pump in a water bath.
  • In vivo studies utilized three pigs, with the pump placed in the descending aorta.
  • Hemodynamic parameters were recorded at varying propeller speeds and sizes.

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Main Results:

  • Bench tests showed velocity-dependent pressure generation, achieving over 22 mm Hg.
  • Maximum flow rates reached 20 L/min at 12,000 rpm and 27 L/min at 15,000 rpm.
  • Animal experiments demonstrated a pressure difference up to 48 mm Hg and increased cardiac output.

Conclusions:

  • The new cardiac assist device is efficient both in vitro and in vivo.
  • The device effectively supports circulation and alters hemodynamics.
  • Performance is directly related to propeller speed and size, indicating potential for clinical application.