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T cell responses to bacterial infection

K M Kerksiek1, E G Pamer

  • 1Sections of Infectious Diseases and Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Current Opinion in Immunology
|August 17, 1999
PubMed

Many exciting advances in our understanding of T cell mediated immunity to bacterial infection have occurred in the past several years. T cell responses have been more fully characterized, due in part to the development of MHC class I tetramers. The importance of cytokines and various effector molecules in defense against infection has come to light. Finally, intracellular bacteria are being exploited to deliver antigens and DNA in an effort to induce immunity to pathogens.

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