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Molecular mechanisms of vertebrate photoreceptor light adaptation
E N Pugh1, S Nikonov, T D Lamb
1FM Kirby Center for Molecular Ophthalmology, Department of Ophthalmology, Institute of Neurological Sciences, Stellar-Chance Laboratories, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, Pennsylvania 19104-6069, USA. pugh@psych.upenn.edu
Current Opinion in Neurobiology
|August 17, 1999
Abstract:
An important recent advance in the understanding of vertebrate photoreceptor light adaptation has come from the discovery that as many as eight distinct molecular mechanisms may be involved, and the realization that one of the principal mechanisms is not dependent on calcium. Quantitative analysis of these mechanisms is providing new insights into the nature of rod photoreceptor light adaptation.