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Related Experiment Videos

Tuberculosis presenting as deep vein thrombosis.

A Gogna1, G R Pradhan, R S Sinha

  • 1Department of Internal Medicine, Safdarjang Hospital, New Delhi, India.

Postgraduate Medical Journal
|August 17, 1999
PubMed
Summary
This summary is machine-generated.

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Two women with deep vein thrombosis (DVT) had enlarged lymph nodes but no cancer. Tuberculosis was found to be the cause of their vena cava obstruction.

Area of Science:

  • Medicine
  • Pathology
  • Radiology

Background:

  • Deep vein thrombosis (DVT) is a serious condition often linked to malignancy or genetic factors.
  • Retroperitoneal lymphadenopathy can cause venous obstruction but is rarely attributed to tuberculosis in this context.
  • Vena cava obstruction presents significant diagnostic challenges.

Observation:

  • Two female patients, aged 21 and 60, presented with DVT.
  • Both cases exhibited significant retroperitoneal, para-aortic, and iliac lymph node enlargement.
  • No evidence of malignancy or other known thrombophilic risk factors was found.

Findings:

  • Investigations confirmed a tubercular etiology for the lymph node enlargement.
  • The enlarged lymph nodes caused vena cava obstruction, leading to DVT.

Related Experiment Videos

  • This suggests tuberculosis as a potential, albeit uncommon, cause of DVT through lymphatic obstruction.

    • Implications:

    • Highlights a rare cause of DVT, emphasizing the need for thorough etiological investigation beyond typical risk factors.
    • Suggests considering tuberculosis in patients with unexplained DVT and retroperitoneal lymphadenopathy.
    • Underscores the importance of integrating infectious disease and vascular medicine perspectives in complex cases.