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Bacterial isolates from patients with preterm labor with and without preterm rupture of the fetal membranes
1Department of Obstetrics and Gynecology, School of Medicine, Gifu University, Gifu-city, Japan. mikamo@cc.gifu-u.ac.jp
Objective:
The aim of this study is to describe the bacterial flora of women in preterm labor with or without premature rupture of membranes.
Methods:
Retrospective studies of 239 patients with preterm labor were performed.
Results:
One hundred and twenty-three of 239 patients with preterm labor (51.5%) had bacterial vaginosis. Seventy of the 239 patients with preterm labor (29.3%) developed premature rupture of the membranes (preterm PROM). Of the 70 patients with preterm PROM, 51 (72.9%) had bacterial vaginosis. Therefore, 51 of the 123 patients with bacterial vaginosis (41.5%) developed preterm PROM. An increased number of organisms detected from the vaginal discharge in patients with preterm labor was associated with preterm PROM by Cochran-Armitage test. An increased number of organisms detected from the vaginal discharge in patients with preterm labor complicated with bacterial vaginosis was significantly associated with preterm PROM by Cochran-Armitage test.
Conclusions:
In preterm labor, the number of different species detected in the vagina provide sensitive and specific prediction of preterm PROM in patients with preterm labor.