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Epithelial cell movements and interactions in limb, neural crest and vasculature
1Department of Anatomy and Physiology, University of Dundee, The Wellcome Trust Building, Dow Street, Dundee, DD1 5EH, UK. c.a.tickle@dundee.ac.uk
Current Opinion in Genetics & Development
|August 17, 1999
Abstract:
Formation of the thickened apical ectodermal ridge of developing vertebrate limbs appears to be a complex process. Direct connections to molecular controls of cell migratory machinery have been shown for first time in neural crest migration. New unsuspected roles are emerging for ephrin ligand/Eph receptor signalling in vascular morphogenesis.