Polarity determination in the Drosophila eye
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Preparation of Adult Drosophila Eyes for Thin Sectioning and Microscopic Analysis
Published on: August 27, 2011
1Developmental Genetics Programme, University of Sheffield, Firth Court, Western Bank, Sheffield, S10 2TN, UK.
Current Opinion in Genetics & Development
|August 17, 1999
Abstract:
In the Drosophila eye, photoreceptor clusters are arranged with mirror-image symmetry about the dorso-ventral midline. Recent work indicates critical rôles for Wingless and JAK/STAT signalling in setting up long-range gradients of positional information that determine this symmetry. Furthermore, important functions have been elucidated for Notch signalling in specifying the position of the axis of symmetry and then later in development in interpreting gradient information.
