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Membrane association with multiple calcium ions: vitamin-K-dependent proteins, annexins and pentraxins
G L Nelsestuen1, B G Ostrowski
1Department of Biochemistry, Molecular Biology and Biophysics University of Minnesota, St Paul, MN 55108, USA. nelse002@maroon.tc.umn.edu
Current Opinion in Structural Biology
|August 17, 1999
Abstract:
Peripheral membrane association with high calcium stoichiometry is shared by three families of proteins: annexins, pentraxins and vitamin-K-dependent proteins. Recent crystal structure determinations, biophysical studies of membrane binding and analyses of protein electrostatic properties offer striking and different concepts for membrane association by each of these protein families.