Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins
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Updated: Oct 19, 2026
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Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases
Published on: August 27, 2021
P Forrer1, S Jung, A Plückthun
1Biochemisches Institut, Universität Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.
Current Opinion in Structural Biology
|August 17, 1999
Abstract:
Phage display of a wide range of polypeptides has been increasingly used to identify novel molecules with useful binding properties for research, medical and industrial applications. Recent developments include methods for the selection of stabilized variants of a protein, the selection of regulatable enzymes and promising strategies for the selection and evolution of protein catalysts.
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