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Related Experiment Videos

Hypomagnesemia in trauma patients.

H Frankel1, R Haskell, S Y Lee

  • 1Department of Traumatology, Brandywine Hospital, 201 Reeceville Road, Coatesville, Pennsylvania 19104, USA.

World Journal of Surgery
|August 18, 1999
PubMed
Summary

Hypomagnesemia is common in injured patients, with 43% showing low magnesium levels. Total magnesium is not a reliable indicator of ionized magnesium in these cases.

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Area of Science:

  • Trauma care
  • Clinical chemistry
  • Critical care medicine

Background:

  • Hypomagnesemia is a frequent electrolyte disturbance in critically ill patients.
  • Accurate assessment of magnesium levels is crucial for appropriate patient management.
  • Existing methods for assessing magnesium may have limitations in specific patient populations.

Purpose of the Study:

  • To determine the incidence of hypomagnesemia in injured patients compared to a general hospital cohort.
  • To compare total magnesium (TMg) and ionized magnesium (IMg) levels.
  • To correlate magnesium levels with injury severity and ethanol levels.

Main Methods:

  • A descriptive study was conducted at a level II trauma center.
  • Consecutive injured patients underwent paired analysis of blood total magnesium (TMg) and ionized magnesium (IMg).

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  • Pearson correlation coefficients were calculated for IMg versus TMg, Injury Severity Score (ISS), Trauma Score (TS), Glasgow Coma Scale (GCS), and blood units transfused.

    • Main Results:

    • 43% of trauma patients had hypomagnesemia, compared to 30% in a general hospital cohort (p<0.05).
    • The correlation between TMg and IMg was weaker at low TMg levels (r(2)=0.35) compared to higher levels (r(2)=0.74).
    • No significant correlation was found between IMg and ISS, TS, GCS, units transfused, or ethanol level.

    Conclusions:

    • Hypomagnesemia is prevalent in injured patients.
    • Total magnesium is an unreliable predictor of ionized magnesium, especially at low levels.
    • Ionized magnesium determination is recommended for accurate diagnosis and management of hypomagnesemia in trauma patients.