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[Myasthenia gravis. Historical aspects].

F M Cunha1, R H Scola, L C Werneck

  • 1Departamento de Clínica Médica do Hospital de Clínicas da Universidade Federal do Paraná (UFPR), Curitiba, Brasil.

Arquivos De Neuro-Psiquiatria
|August 18, 1999
PubMed
Summary
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This paper explores the history of myasthenia gravis, from its 1672 description by Sir Thomas Willis to early management challenges. It details historical facts, initial treatments, and lesser-known curiosities of this neuromuscular disorder.

Area of Science:

  • Neurology
  • Medical History

Context:

  • Myasthenia gravis is a chronic autoimmune neuromuscular disease.
  • Understanding its historical context is crucial for appreciating modern treatment advancements.

Purpose:

  • To provide a historical overview of myasthenia gravis.
  • To highlight early diagnostic and management challenges.
  • To present unique historical facts and curiosities.

Summary:

  • The study traces the history of myasthenia gravis from its initial description in 1672 by Sir Thomas Willis.
  • It examines the difficulties encountered in managing and treating the first diagnosed patients.
  • The paper includes historical details on the investigation and early therapeutic approaches to myasthenia gravis.

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Impact:

  • Offers insights into the evolution of understanding and treating myasthenia gravis.
  • Enriches the medical literature with historical perspectives.
  • Provides context for current research and clinical practice in neuromuscular diseases.