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Related Experiment Videos

Synthetic hydroxyapatite orbital implants: a clinical and MRI evaluation.

N Sarvananthan1, A J Liddicoat, G T Fahy

  • 1Department of Ophthalmology, Leicester Royal Infirmary, UK.

Eye (London, England)
|August 18, 1999
PubMed
Summary

Synthetic hydroxyapatite orbital implants offer good cosmetic results. However, vascularization of these implants is variable, particularly in secondary implantation surgeries, impacting long-term integration.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Medical Imaging

Background:

  • Coralline hydroxyapatite orbital implants have been utilized since the 1980s.
  • Synthetic hydroxyapatite (HA) implants are increasingly used for both primary and secondary orbital implantation.
  • These implants may require drilling and pegging post-vascularization.

Purpose of the Study:

  • To evaluate the clinical outcomes of synthetic hydroxyapatite orbital implants.
  • To assess the vascularization of synthetic hydroxyapatite orbital implants using MRI.

Main Methods:

  • Clinical evaluation of twelve patients with synthetic HA orbital implants.
  • Orbital magnetic resonance imaging (MRI) with gadolinium contrast in 8 patients at least 9 months post-operation.

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  • Comparison between primary (n=6) and secondary (n=6) implant cases.

    • Main Results:

    • No significant complications were reported with synthetic HA implants.
    • All patients expressed cosmetic satisfaction with the surgical outcomes.
    • MRI showed inhomogeneous enhancement in primary implants and poor enhancement in most secondary implants.

    Conclusions:

    • Synthetic hydroxyapatite implants provide favorable clinical and cosmetic results.
    • Vascularization of synthetic HA implants is inconsistent, especially in secondary cases.
    • Further research may be needed to optimize vascularization in secondary HA orbital implants.