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Vertebral osteomyelitis associated with cat-scratch disease.

C V Hulzebos1, H A Koetse, J L Kimpen

  • 1Department of Pediatrics, Beatrix Children's Hospital, Groningen University Hospital, The Netherlands. c.hulzebos@bkk.azg.nl

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 18, 1999
PubMed
Summary

Cat-scratch disease (CSD) can cause vertebral osteomyelitis and soft-tissue infections. Prompt antibiotic treatment led to full recovery, despite persistent radiographic bone lesions.

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Area of Science:

  • Infectious Diseases
  • Orthopedics
  • Radiology

Background:

  • Vertebral osteomyelitis is a serious infection of the spine.
  • Cat-scratch disease (CSD), caused by Bartonella henselae, typically presents with lymphadenopathy.
  • CSD-associated vertebral osteomyelitis is a rare but significant clinical manifestation.

Observation:

  • A case of vertebral osteomyelitis and paravertebral soft-tissue collections secondary to CSD is presented.
  • Diagnosis was confirmed via histology, serology, and PCR.
  • Radiographic evidence of skeletal lesions persisted post-treatment.

Findings:

  • Antibiotic therapy resulted in complete clinical recovery for the patient.
  • A review of 15 additional cases of CSD-associated osteomyelitis is included.

Related Experiment Videos

  • Bartonella henselae should be considered in the differential diagnosis of vertebral osteomyelitis.

    • Implications:

    • Early diagnosis and appropriate antibiotic management are crucial for favorable outcomes in CSD-related osteomyelitis.
    • This case highlights the diverse spectrum of CSD manifestations.
    • Further research into optimal treatment durations and long-term sequelae is warranted.