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[Predonation and transfusion in open heart surgery]
H Minami1, N Wakita, T Kawahira
1Department of Cardiovascular Surgery, Kobe Rosai Hospital, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 24, 1999
Summary
Autologous blood predonation significantly reduces the need for homologous blood transfusions in open-heart surgery. Predonating 800 ml of autologous blood may eliminate the need for homologous transfusions.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
- Anesthesiology
Background:
- Open-heart surgery frequently requires blood transfusions, increasing risks and costs.
- Autologous blood predonation is a strategy to mitigate homologous blood use.
Purpose of the Study:
- To evaluate the efficacy of autologous blood predonation in reducing homologous blood transfusions during open-heart surgery.
Main Methods:
- A prospective study of 100 open-heart surgeries (CABG, valve, ASD, myxoma) was conducted.
- Inclusion criteria for autologous predonation: age < 70, weight > 40 kg, hemoglobin > 12 g/dl.
- Exclusion criteria: NYHA class IV, emergency operations.
Main Results:
- Only 36.6% of patients with autologous predonation required homologous transfusions, compared to 63.4% without.
- Homologous transfusion rates were 5% for 800 ml predonation, 69% for 400 ml, and 71% for 200 ml.
- Blood loss was not significantly dependent on sex or age.
Conclusions:
- Autologous blood predonation is effective in reducing homologous blood requirements for open-heart surgery.
- Predonation of 800 ml appears sufficient to avoid blood transfusions in many open-heart procedures.