[In vitro bactericidal action of dissolved ozone on different strains of Mycobacterium tuberculosis]

The mycobacterium tuberculosis (MBT) strains H37 Rv (USA and Czechoslovakia), Erdman, and multiresistant clinical strain 2255 having different milliliter levels of microbes were kept in the soluble ozone at the concentrations of 1-4 micrograms/ml for 30 and 60 minutes. The soluble ozone-treated strains were cultured in the Finn-I medium. The soluble ozone at the concentration was found to produce bactericidal and bacteriostatic effects on MBT, including multiresistant strains. The MBT strains resistant to antituberculosis agents were also more resistant to soluble ozone; however, longer exposure to the "therapeutical" concentrations of soluble ozone proved to damage multiresistant strains.