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Anabolic steroids.
1Department of Pulmonology, University Hospital Maastricht, The Netherlands. e.creutzberg@pul.unimaas.nl
Current Opinion in Clinical Nutrition and Metabolic Care
|August 24, 1999
Summary
Anabolic steroid therapy can promote muscle growth and improve outcomes in wasting diseases. This review covers their use, mechanisms, clinical trials, and side effects in disease management.
Area of Science:
- Endocrinology
- Metabolism
- Pharmacology
Background:
- Wasting diseases, both acute and chronic, present significant challenges in patient management.
- Promoting anabolism is crucial for improving clinical outcomes in these conditions.
Purpose of the Study:
- To review the rationale for using anabolic steroids in acute and chronic wasting diseases.
- To discuss the mechanistic actions, clinical evidence, and side effects of anabolic steroid treatment.
Main Methods:
- Literature review of existing studies on anabolic steroids in wasting conditions.
- Analysis of clinical trial data regarding efficacy and safety.
- Examination of the physiological mechanisms of anabolic steroids.
Main Results:
- Anabolic steroids demonstrate potential as an intervention to enhance anabolism.
- Clinical trials provide evidence for their role in improving outcomes in specific wasting diseases.
- Understanding of mechanistic actions is expanding.
Conclusions:
- Anabolic steroid treatment offers a viable therapeutic option for managing acute and chronic wasting diseases.
- Further research may refine treatment protocols and expand applications.
- Careful consideration of side effects is essential for safe and effective use.