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Tumor angiogenesis in patients with laryngeal cancer
K Kupisz1, D Chibowski, J Klatka
1Department of Otolaryngology, University Medical School of Lublin, Poland.
Abstract:
Tumor angiogenesis was evaluated in 60 patients with primary laryngeal cancer by quantitating the microvessel density with antibodies against factor VIII. The microvessel density was then correlated with T stage, N stage, histologic grade and patient survival. A direct correlation was found between increased tumor angiogenesis and T stage, histologic grade and a shorter survival rate.