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Childhood functional gastrointestinal disorders
A Rasquin-Weber1, P E Hyman, S Cucchiara
1Committee on Childhood Functional Gastrointestinal Disorders, Multinational Working Teams to Develop Criteria for Functional Disorders (Rome II), University of Montreal, Quebec, Canada.
Insights
This study introduces the first criteria for pediatric functional gastrointestinal disorders (FGIDs), organizing them by main complaints. It provides a reference for diagnosing FGIDs in infants, children, and adolescents.
Area of Science:
- Pediatric Gastroenterology
- Functional Gastrointestinal Disorders
- Clinical Criteria Development
Background:
- Functional gastrointestinal disorders (FGIDs) in children lack standardized diagnostic criteria.
- Existing adult FGID criteria are not directly applicable to developing pediatric physiology and cognitive stages.
- A consensus-based approach is needed to define FGIDs in pediatric populations.
Purpose of the Study:
- To establish the first set of diagnostic criteria for FGIDs in infancy, childhood, and adolescence.
- To create a practical reference for clinicians diagnosing pediatric FGIDs.
- To adapt and classify FGIDs relevant to pediatric development and symptom reporting.
Main Methods:
- A consensus-building process based on clinical experience, mirroring adult FGID criteria development.
- Classification organized by main patient complaints rather than organ systems.
- Review and adaptation of existing FGID criteria for pediatric applicability.
Main Results:
- A novel classification system for pediatric FGIDs is proposed, differing from adult organ-targeted systems.
- Specific pediatric FGIDs identified include toddler's diarrhea, functional constipation, and infant dyschezia.
- Disorders like irritable bowel syndrome (IBS) and functional dyspepsia are adapted from adult criteria due to sufficient pediatric data.
Conclusions:
- The developed criteria provide a foundational framework for diagnosing pediatric FGIDs.
- Some FGIDs require age-specific considerations due to developmental and behavioral factors.
- Further research is needed for pediatric FGIDs not yet included, such as functional biliary disorders.
Abstract:
This is the first attempt at defining criteria for functional gastrointestinal disorders (FGIDs) in infancy, childhood, and adolescence. The decision-making process was as for adults and consisted of arriving at consensus, based on clinical experience. This paper is intended to be a quick reference. The classification system selected differs from the one used in the adult population in that it is organized according to main complaints instead of being organ-targeted. Because the child is still developing, some disorders such as toddler's diarrhea (or functional diarrhea) are linked to certain physiologic stages; others may result from behavioral responses to sphincter function acquisition such as fecal retention; others will only be recognizable after the child is cognitively mature enough to report the symptoms (e.g., dyspepsia). Infant regurgitation, rumination, and cyclic vomiting constitute the vomiting disorders. Abdominal pain disorders are classified as: functional dyspepsia, irritable bowel syndrome (IBS), functional abdominal pain, abdominal migraine, and aerophagia. Disorders of defecation include: infant dyschezia, functional constipation, functional fecal retention, and functional non-retentive fecal soiling. Some disorders, such as IBS and dyspepsia and functional abdominal pain, are exact replications of the adult criteria because there are enough data to confirm that they represent specific and similar disorders in pediatrics. Other disorders not included in the pediatric classification, such as functional biliary disorders, do occur in children; however, existing data are insufficient to warrant including them at the present time. For these disorders, it is suggested that, for the time being, clinicians refer to the criteria established for the adult population.
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