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Related Experiment Videos

Towards a composite scoring solution for the Neurobehavioral Functioning Inventory.

K P Weinfurt1, R Willke, H A Glick

  • 1Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC 20007, USA.

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
|August 24, 1999
PubMed
Summary

This study developed and validated the Neurobehavioral Functioning Inventory for head injury patients. The new scale effectively measures cognitive deficits, depression, aggression, and somatization, correlating with quality of life and clinical severity.

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Area of Science:

  • Neuroscience
  • Clinical Psychology
  • Rehabilitation Medicine

Background:

  • Limited research exists on quality of life measures specific to head/brain injury populations.
  • Existing general quality of life measures may not adequately capture the unique challenges faced by individuals with head injuries.

Purpose of the Study:

  • To develop and evaluate a disease-specific measure for quality of life in head/brain injury populations.
  • To reduce the Neurobehavioral Functioning Inventory (NFI) into a smaller set of composite scales.
  • To assess the reliability and validity of the NFI scales in a large, international clinical trial.

Main Methods:

  • Principal components analysis was used to reduce the 66-item NFI into composite scales.
  • Four symptom categories were identified: cognitive deficits, depression, aggression, and somatization.

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  • Internal reliabilities (alpha coefficient) and correlations with quality of life and clinical severity were calculated.

    • Main Results:

    • Four reliable scales were constructed from the NFI with acceptable internal reliabilities (alpha range = 0.79-0.92).
    • All four scales significantly correlated with patient-rated overall quality of life.
    • Cognitive deficits, depression, and somatization scales significantly correlated with overall clinical severity.

    Conclusions:

    • The developed NFI scales provide a reliable and valid measure of quality of life for head injury populations.
    • These disease-specific scales can aid in assessing the impact of head injuries on various aspects of well-being.
    • Further formal evaluation of this and other disease-specific measures is warranted for clinical application.