Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proliferative verrucous leukoplakia with cutaneous involvement.

J C Haley1, A F Hood, G W Mirowski

  • 1Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis 46202, USA.

Journal of the American Academy of Dermatology
|August 25, 1999
PubMed
Summary

Proliferative verrucous leukoplakia (PVL), a rare oral condition with high cancer risk, has now been observed in the skin. This case report highlights a novel presentation of PVL beyond its typical oral location.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of sodium lactate and vinegar derivatives on the quality of fresh Italian pork sausage links.

Meat science·2014
Same author

Genetics in the medical curriculum.

Journal. Association of American Medical Colleges·2010
Same author

Lichen sclerosus-lichen planus overlap in a patient with hepatitis C virus infection.

The British journal of dermatology·2004
Same author

Gardner syndrome.

Journal of the American Academy of Dermatology·2001
Same author

Neurofibromatosis type 2.

Journal of the American Academy of Dermatology·2001
Same author

Human papillomavirus: clinical significance and malignant potential.

International journal of dermatology·2001

Area of Science:

  • Dermatology
  • Oral Pathology
  • Oncology

Background:

  • Proliferative verrucous leukoplakia (PVL) is a recognized oral potentially malignant disorder.
  • PVL is histologically characterized by a high risk of malignant transformation into verrucous squamous cell carcinoma.
  • Previous literature has exclusively documented PVL within the oral cavity.

Observation:

  • This report details an unprecedented case of PVL occurring on the skin (cutaneous PVL).
  • The clinical and histological presentation of this cutaneous PVL is described.
  • This finding expands the known anatomical distribution of PVL.

Findings:

  • The study confirms the existence of cutaneous PVL, a previously unreported entity.
  • Histopathological analysis revealed features consistent with PVL in a skin lesion.

Related Experiment Videos

  • This challenges the established understanding of PVL's typical localization.

    • Implications:

    • The findings suggest that PVL may not be exclusively an oral condition.
    • This broadens the differential diagnosis for verrucous skin lesions.
    • Further research is warranted to understand the pathogenesis and behavior of cutaneous PVL.