[Treatment of peritonitis using ozone and hydropressive technology]

Area of Science:

• Surgical Innovation
• Infectious Disease Management
• Gastroenterology

Background:

• Acute peritonitis presents a high mortality rate, necessitating advanced treatment strategies.
• Current treatments for severe peritonitis often have limitations in managing microbial load and systemic effects.
• Developing novel therapeutic approaches is crucial for improving patient outcomes.

Purpose of the Study:

• To develop and evaluate novel methods for treating severe acute peritonitis.
• To assess the efficacy of ozone therapy and hydropressive treatment in managing abdominal infections.
• To compare the outcomes of the new treatment protocol against a control group.

Main Methods:

• Experimental validation using mongrel dogs and white rats.
• Clinical application in 94 patients with severe acute peritonitis.
• Utilizing microdisperse stream of ozonated solution under pressure for abdominal cavity treatment.
• Implementing intestinal ozone dialysis for microbial reduction.

Main Results:

• High antimicrobial effect observed with ozonated solution under pressure.
• Intestinal ozone dialysis reduced microbial bodies in 65% of patients by 2-3 times.
• Paresis elimination time decreased 3-4 times, with faster resolution of endogenous intoxication.
• Mortality rate reduced from 62.07% in the control group to 37.23% in the test group.

Conclusions:

• Ozone therapy and hydropressive treatment are effective in combating abdominal infections.
• The developed treatment program significantly improves patient recovery and survival rates.
• These methods offer a promising alternative for managing severe acute peritonitis.