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Related Experiment Videos

Declarative and procedural memory in bipolar disorder.

W G van Gorp1, L Altshuler, D C Theberge

  • 1Cornell University Medical College, New York, NY 10021, USA.

Biological Psychiatry
|August 25, 1999
PubMed
Summary
This summary is machine-generated.

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Bipolar disorder patients show deficits in declarative memory but not procedural learning. This suggests specific brain region involvement, impacting memory function in bipolar disorder.

Area of Science:

  • Neuropsychology
  • Cognitive Neuroscience
  • Psychiatry

Background:

  • Memory function is under-researched in bipolar disorder.
  • Previous studies indicate declarative memory deficits in euthymic bipolar patients.

Purpose of the Study:

  • Investigate declarative and procedural learning/memory in bipolar patients.
  • Compare bipolar patients (with/without alcohol abuse) to controls in an euthymic state.

Main Methods:

  • Administered California Verbal Learning Test, Star Mirror Tracing Task, Pursuit Rotor Task, American National Adult Reading Test, and WAIS-R Vocabulary Subtest.
  • Utilized blinded researchers to assess bipolar patients and control subjects.

Main Results:

  • Bipolar patients exhibited poorer declarative memory (California Verbal Learning Test) than controls.

Related Experiment Videos

  • No significant differences were found in procedural learning tasks (Pursuit Rotor Task, Star Mirror Task) between groups.

    • Conclusions:

    • Findings suggest impaired temporal lobe function in bipolar disorder.
    • Results do not indicate basal ganglia dysfunction in memory processing for bipolar patients.