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Morbidity and mortality after pneumonectomy.

J Klemperer1, R J Ginsberg

  • 1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

Chest Surgery Clinics of North America
|August 25, 1999
PubMed
Summary

Pneumonectomy, a major lung surgery, carries a 5-10% mortality risk and higher complication rates, especially for complex cases or benign diseases. Risk factors for poor outcomes are reviewed.

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Area of Science:

  • Thoracic Surgery
  • Surgical Outcomes
  • Cardiopulmonary Complications

Background:

  • Pneumonectomy, the surgical removal of an entire lung, remains a high-risk thoracic procedure despite advances in perioperative care.
  • Modern series report a 30-day mortality rate between 5% and 10% following pneumonectomy.
  • Complex pneumonectomies and those performed for benign conditions are associated with even higher mortality rates.

Purpose of the Study:

  • To review the risk factors associated with poor outcomes after pneumonectomy.
  • To highlight the inherent risks and complications associated with this major thoracic surgery.

Main Methods:

  • Review of existing literature and modern series reporting on pneumonectomy outcomes.
  • Identification and categorization of known risk factors for adverse events.
  • Analysis of complication rates compared to lesser lung resections.

Main Results:

  • Pneumonectomy is associated with a significant 30-day mortality rate of 5% to 10%.
  • Complication rates, particularly cardiopulmonary issues, are higher than with less extensive lung resections.
  • Specific risk factors contributing to poorer outcomes have been identified and are discussed.

Conclusions:

  • Pneumonectomy is a high-risk surgical intervention requiring careful patient selection and management.
  • Understanding and mitigating identified risk factors are crucial for improving patient outcomes.
  • The procedure is linked to a notable incidence of cardiopulmonary complications.

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