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Sepsis
1Johns Hopkins Oncology Center, Baltimore, MD, USA.
Objectives:
To review infection and sepsis in patients with cancer and to provide an overview of controversies and research-based practices of infectious complications and management strategies.
Data Sources:
Research studies, review articles, web sites, and consensus documents.
Conclusions:
Traditional assumptions about infection and its optimal management are redefined by research regarding transfusion and catheter-related infections, prophylactic antibiotic administration, use of growth factors, and antimicrobial therapy regimens.
Implications For Nursing Practice:
Infection is still the most common source of morbidity and mortality among cancer patients. The importance of recognizing high-risk patients, implementing infection prevention practices, and prompt intervention for infection symptoms has been established.